MOTS-C 10mg Peptide
In stock
Supplied for Research Purposes Only. This product and the information provided are intended solely for laboratory research. We do not provide guidance on human use. These products are for sale to persons aged 18 and over only. Customers are responsible for checking the legal status of the product in their own jurisdiction before purchase.
MOTS-c 10mg is a research vial of a 16-amino-acid mitochondrial-derived peptide. Studies explore metabolic adaptation, AMPK-related signalling and skeletal-muscle responses, with a particularly interesting connection to exercise physiology.
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MOTS-c and mitochondrial signalling
MOTS-c 10mg relates to a peptide encoded within the mitochondrial 12S ribosomal RNA region. Its discovery helped establish mitochondria as sources of regulatory peptides, adding a signalling role to their familiar involvement in cellular energy production.
Metabolic adaptation in experimental models
Foundational studies linked MOTS-c to folate and purine metabolism, AMPK activation and insulin sensitivity. In mice, researchers reported effects on diet-related metabolic disturbances. Subsequent work investigated skeletal-muscle stress responses and physical performance in animals of different ages.
These findings provide a focused basis for studying how a short mitochondrial peptide influences communication between metabolism, muscle function and adaptive responses to stress.
The exercise connection in humans
Human studies have measured endogenous MOTS-c around exercise. One investigation found increases in muscle and circulation following an exercise challenge, while another observed only a trend in circulating levels after endurance activity. The differing observations make exercise type, sampling and participant characteristics relevant research questions.
Human biomarker studies and mouse administration experiments contribute different kinds of evidence. Together they support interest in MOTS-c biology, while benefits from administering the peptide to people remain to be established.
Also known as / branded as
- MOTS-c
- Mitochondrial open reading frame of the 12S rRNA type-c
