Semax 10mg

Semax and neurotrophic research

Semax 10mg is the synthetic heptapeptide Met-Glu-His-Phe-Pro-Gly-Pro, often written ACTH(4-7)PGP. Its research profile centres on the nervous system, including signalling pathways involved in neuronal plasticity and responses to injury.

BDNF and the TrkB pathway

Brain-derived neurotrophic factor, or BDNF, and its receptor TrkB are important components of neuronal signalling. In a rat hippocampus study, Semax exposure was associated with increases in BDNF protein and changes in TrkB activation and gene expression. Behavioural measurements in the same work added a functional dimension to those molecular observations.

This combination of biochemical and behavioural endpoints explains Semax's relevance to learning and memory research. The findings belong to an animal model and do not establish a cognitive benefit in human users.

Responses to cerebral ischaemia

Further experiments have investigated gene-expression changes after reduced blood supply to the brain. Human reports have also examined Semax in stroke rehabilitation, including motor outcomes and BDNF measurements. These different evidence layers help define questions for continuing neuropeptide research.

The 10mg quantity identifies this product variant. It does not imply a different molecular mechanism or a demonstrated advantage over the 5mg research listing.

Also known as / branded as

• ACTH(4-7)-Pro-Gly-Pro
• ACTH(4-7)PGP
• Met-Glu-His-Phe-Pro-Gly-Pro
• MEHFPGP