SARM Showdown: Best SARMs for Strength — S-23 vs YK-11 vs RAD-140
When people look for strength-focused SARMs, three compounds are mentioned more than any others: S-23, YK-11 and RAD-140. Each is known for strong performance outcomes in research environments, but they achieve this in different ways.
This breakdown looks at what each compound is, how it is commonly discussed in the research community, and how they compare side by side for strength-focused goals.
Disclaimer: All information is for educational and research purposes only.
S-23 - High-Power Selective Androgen Receptor Modulator
S-23 is often described as one of the most potent SARMs investigated so far. It shows a strong affinity for the androgen receptor and is typically associated with:
Highly anabolic activity in research
Notable strength improvements within short timeframes (commonly referenced anecdotally)
A dry, dense, hardened appearance in user reports
A reputation for being the strongest traditional SARM
S-23 is usually considered the most direct and aggressive strength-focused compound.
YK-11 - Myostatin-Inhibiting Androgen Derivative
YK-11 is not a classic SARM but is grouped with them due to its receptor interaction. It is notable for early research suggesting myostatin-inhibiting activity. It is often described as:
Increasing lean mass rapidly
Driving strength progression through possible myostatin suppression
Producing size and strength together rather than a lean strength profile
Showing quick adaptations in anecdotal performance discussions
Where S-23 is about raw power output, YK-11 is more aligned with strength combined with visible size increases.
RAD-140 (Testolone) - Balanced Strength and Performance
RAD-140 sits between the two extremes and is often seen as the balanced strength compound. It is commonly referenced for:
Strong anabolic effects in early studies
Clear improvements in training performance
Supporting lean mass without excess water retention
Being dependable and well-rounded compared to more extreme options
RAD-140 is frequently chosen as the middle-ground strength compound.
Strength Comparison
Raw Strength (Low Rep Power)
Winner: S-23
S-23 is regularly described as producing the most immediate strength-focused results.
Strength Plus Size
Winner: YK-11
Its reputation for affecting myostatin gives it a strong position in size and strength combinations.
Balanced Strength and Lean Mass
Winner: RAD-140
Strong overall performance without the extremes of S-23 or YK-11.
Which Compound Fits Which Research Goal
Maximum strength intensity:
S-23
Strength and muscle size together:
YK-11
Balanced strength and lean mass:
RAD-140
All three compounds have distinct profiles and none are universally the best. The most suitable option depends entirely on the focus of the research being carried out.
