Epithalon 10mg Peptide

Epithalon in cellular-ageing research

Epithalon 10mg is the synthetic tetrapeptide Ala-Glu-Asp-Gly, abbreviated AEDG. Also spelled Epitalon, it developed from research on pineal peptide preparations and has become a subject of interest in telomere biology.

Telomerase and telomere maintenance

Telomeres are protective structures at chromosome ends, and telomerase is one of the mechanisms involved in their maintenance. A 2003 experiment reported telomerase activation and telomere elongation in cultured human fetal fibroblasts following Epithalon exposure.

A later cell-line study examined hTERT expression, telomerase activity and alternative lengthening of telomeres. It reported responses in both normal and cancer-derived cells, with differences in the pathways involved. This adds mechanistic detail and shows why cell type matters when interpreting a telomere result.

A defined peptide within a wider research field

The broader pineal-peptide literature also explores ageing and hormonal rhythms in experimental animals. Epithalon should be distinguished from Epithalamin, a mixed pineal extract: their histories are connected, but they are not the same substance.

These findings make Epithalon relevant to laboratory research on cellular ageing and chromosome maintenance. Cell-culture changes and animal observations do not yet establish lifespan extension or age reversal in humans.

Also known as / branded as

• Epitalon
• AEDG
• Ala-Glu-Asp-Gly