Kisspeptin-10 10mg Peptide

Kisspeptin-10 and reproductive signalling

Kisspeptin-10 10mg is the ten-amino-acid receptor-active fragment of the KISS1 peptide family. It activates KISS1R, historically known as GPR54, and helps researchers study the upstream regulation of gonadotropin-releasing hormone, or GnRH.

Human studies of hormone release

Physiological studies in healthy men have reported increased luteinising hormone secretion and changes in LH pulse frequency following kisspeptin-10 exposure. These measurements provide a way to investigate the timing as well as the magnitude of reproductive hormone signals.

Comparisons between men and women have also shown the importance of sex and menstrual-cycle context. This makes kisspeptin-10 particularly interesting for questions about how reproductive state shapes responsiveness within the hypothalamic-pituitary-gonadal axis.

Different lengths, related sequences

Kisspeptin-10 and kisspeptin-54 share the active C-terminal sequence but differ in length. Direct comparisons have investigated their hormone responses, while the shorthand KISS1(112-121) and metastin(45-54) identifies the ten-residue fragment using different numbering systems.

These studies establish a meaningful human physiological research context. Hormone responses remain distinct from outcomes such as pregnancy, sustained testosterone restoration or improved sexual function, which need their own compound-specific evidence.

Also known as / branded as

• KP-10
• Kp-10
• KISS1(112-121)-NH2
• Kisspeptin(112-121)
• Metastin(45-54)
• Metastin(10)